Chymotrypsin, Urease Inhibitory and Antioxidant Activities of Malva neglecta Wallr.

نویسندگان

چکیده

Amaç: Bu araştırmada Malva neglecta Wallr.’nın kimotripsin ve üreaz enzimlerini inhibe edici aktivitesinin tespiti ayrıca antioksidan aktivitesi, toplam fenol flavonoit içeriğinin belirlenmesi amaçlanmıştır. Yöntem: 2021 yılı Nisan-Haziran ayları arasında bitkinin çiçekli meyveli toprak üstü kısımlarından metanol su ekstresi hazırlanmış bu ekstrelerin in vitro inhibitör aktivitesi belirlenmiştir. Antioksidan aktivitenin için ABTS, CUPRAC DPPH yöntemleri kullanılmıştır. Toplam içerikleri ise sırasıyla Folin Ciocalteu aluminyum klorür kolorimetrik kullanılarak Bulgular: Metanol önemli düzeyde aktivite göstermiştir (IC50: 67.67 µg/mL); enzimi üzerinde hem orta etki (sırasıyla %36.52 34.38 inhibisyon). testlerinde daha yüksek sergilerken; ABTS testinde radikal süpürücü göstermiştir. elde edilen sonuçlarla paralel olarak ekstresinin olduğu anlaşılmıştır (42.93 mg rutin eşdeğeri/g). Sonuç: Sonuç M. kuvvetli ile dikkat çekmiştir. Üreaz flavanoit içeriğiyle de dikkate alındığında bitki kapsamlı çalışmaların yapılması gerektiği sonucuna varılmıştır.

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ژورنال

عنوان ژورنال: Mersin üniversitesi t?p fakültesi lokman hekim dergisi

سال: 2023

ISSN: ['1309-8004', '1309-761X']

DOI: https://doi.org/10.31020/mutftd.1266561